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Gene: UPF2 (UPF2 regulator of nonsense mediated mRNA decay) Homo sapiens
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Symbol: UPF2
Name: UPF2 regulator of nonsense mediated mRNA decay
CRRD ID: 1319373
Description: Exhibits telomeric DNA binding activity. Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Localizes to cytoplasmic ribonucleoprotein granule; cytosol; and exon-exon junction complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp434D222; FRS2/UPF2/LEMD3 fusion; HUPF2; KIAA1408; LEMD3/UPF2 fusion; MGC138834; MGC138835; nonsense mRNA reducing factor 2; regulator of nonsense transcripts 2; RENT2; smg-3; smg-3 homolog, nonsense mediated mRNA decay factor; up-frameshift suppressor 2 homolog; UPF2 regulator of nonsense transcripts homolog; UPF2 regulator of nonsense transcripts homolog (yeast); UPF2, regulator of nonsense mediated mRNA decay; yeast Upf2p homolog
Orthologs:
Mus musculus (house mouse) : Upf2 (UPF2 regulator of nonsense transcripts homolog (yeast))  MGI  Alliance
Rattus norvegicus (Norway rat) : Upf2 (UPF2, regulator of nonsense mediated mRNA decay)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Upf2 (UPF2 regulator of nonsense mediated mRNA decay)
Pan paniscus (bonobo/pygmy chimpanzee) : UPF2 (UPF2 regulator of nonsense mediated mRNA decay)
Canis lupus familiaris (dog) : UPF2 (UPF2 regulator of nonsense mediated mRNA decay)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Upf2 (UPF2 regulator of nonsense mediated mRNA decay)
Sus scrofa (pig) : UPF2 (UPF2 regulator of nonsense mediated mRNA decay)
Chlorocebus sabaeus (African green monkey) : UPF2 (UPF2 regulator of nonsense mediated mRNA decay)
Heterocephalus glaber (naked mole-rat) : Upf2 (UPF2 regulator of nonsense mediated mRNA decay)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1011,920,022 - 12,043,170 (-)EnsemblGRCh38hg38GRCh38
GRCh381011,920,022 - 12,043,170 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371011,962,021 - 12,085,169 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361012,002,027 - 12,125,029 (-)NCBINCBI36hg18NCBI36
Build 341012,002,027 - 12,125,029NCBI
Celera1011,890,782 - 12,013,775 (-)NCBI
Cytogenetic Map10p14NCBI
HuRef1011,879,153 - 12,002,622 (-)NCBIHuRef
CHM1_11011,961,725 - 12,085,128 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Nomenclature History
 
More on UPF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319373
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.