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Gene: Shc4 (SHC (Src homology 2 domain containing) family, member 4) Mus musculus
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Symbol: Shc4
Name: SHC (Src homology 2 domain containing) family, member 4
Description: Exhibits protein domain specific binding activity and receptor tyrosine kinase binding activity. Involved in several processes, including apoptotic process; positive regulation of cell population proliferation; and stem cell differentiation. Predicted to localize to the plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; heart; sensory organ; and skin. Orthologous to human SHC4 (SHC adaptor protein 4); PARTICIPATES IN chronic myeloid leukemia pathway; epidermal growth factor/neuregulin signaling pathway; glioma pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6230417E10Rik; 9930029B02Rik; Gm685; mShcD; novel phosphotyrosine interaction domain (PTB/PID) and SH2 domains containing protein; rai-like protein RaLP; RaLP; RP23-323D9.1; SH2 domain protein C4; SHC-transforming protein 4; SHC-transforming protein D; src homology 2 domain-containing-transforming protein C4
Orthologs:
Homo sapiens (human) : SHC4 (SHC adaptor protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Shc4 (SHC adaptor protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shc4 (SHC adaptor protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SHC4 (SHC adaptor protein 4)
Canis lupus familiaris (dog) : SHC4 (SHC adaptor protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shc4 (SHC adaptor protein 4)
Sus scrofa (pig) : SHC4 (SHC adaptor protein 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382125,627,439 - 125,724,148 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372125,453,183 - 125,549,884 (-)NCBIGRCm37mm9NCBIm37
MGSCv362125,318,888 - 125,415,589 (-)NCBImm8
Celera2126,873,463 - 126,969,748 (-)NCBICelera
Cytogenetic Map2 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Shc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319380
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.