Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Malt1 (MALT1 paracaspase) Mus musculus
Symbol: Malt1
Name: MALT1 paracaspase
Description: Exhibits protease binding activity. Predicted to contribute to kinase activator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of NF-kappaB transcription factor activity; and positive regulation of immune response. Localizes to cytosol and polkadots. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in lymphoma; non-Hodgkin lymphoma; and primary immunodeficiency disease. Orthologous to human MALT1 (MALT1 paracaspase); PARTICIPATES IN nuclear factor kappa B signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630046N12; D430033E09Rik; MGC124469; MGC124470; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; paracaspase; paracaspase-1; Pcasp1
Homo sapiens (human) : MALT1 (MALT1 paracaspase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Malt1 (MALT1 paracaspase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Malt1 (MALT1 paracaspase)
Pan paniscus (bonobo/pygmy chimpanzee) : MALT1 (MALT1 paracaspase)
Canis lupus familiaris (dog) : MALT1 (MALT1 paracaspase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Malt1 (MALT1 paracaspase)
Sus scrofa (pig) : MALT1 (MALT1 paracaspase)
Chlorocebus sabaeus (African green monkey) : MALT1 (MALT1 paracaspase)
Heterocephalus glaber (naked mole-rat) : Malt1 (MALT1 paracaspase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1865,430,938 - 65,479,067 (+)EnsemblGRCm38mm10GRCm38
GRCm381865,430,939 - 65,478,888 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371865,590,651 - 65,638,446 (+)NCBIGRCm37mm9NCBIm37
MGSCv361865,556,366 - 65,604,161 (+)NCBImm8
Celera1866,699,207 - 66,748,598 (+)NCBICelera
Cytogenetic Map18E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Malt1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319402
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.