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Gene: Malt1 (MALT1 paracaspase) Mus musculus
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Symbol: Malt1
Name: MALT1 paracaspase
Description: Exhibits protease binding activity. Predicted to contribute to kinase activator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of NF-kappaB transcription factor activity; and positive regulation of immune response. Localizes to cytosol and polkadots. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in lymphoma; non-Hodgkin lymphoma; and primary immunodeficiency disease. Orthologous to human MALT1 (MALT1 paracaspase); PARTICIPATES IN nuclear factor kappa B signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630046N12; D430033E09Rik; MGC124469; MGC124470; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; paracaspase; paracaspase-1; Pcasp1
Orthologs:
Homo sapiens (human) : MALT1 (MALT1 paracaspase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Malt1 (MALT1 paracaspase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Malt1 (MALT1 paracaspase)
Pan paniscus (bonobo/pygmy chimpanzee) : MALT1 (MALT1 paracaspase)
Canis lupus familiaris (dog) : MALT1 (MALT1 paracaspase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Malt1 (MALT1 paracaspase)
Sus scrofa (pig) : MALT1 (MALT1 paracaspase)
Chlorocebus sabaeus (African green monkey) : MALT1 (MALT1 paracaspase)
Heterocephalus glaber (naked mole-rat) : Malt1 (MALT1 paracaspase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1865,430,938 - 65,479,067 (+)EnsemblGRCm38mm10GRCm38
GRCm381865,430,939 - 65,478,888 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371865,590,651 - 65,638,446 (+)NCBIGRCm37mm9NCBIm37
MGSCv361865,556,366 - 65,604,161 (+)NCBImm8
Celera1866,699,207 - 66,748,598 (+)NCBICelera
Cytogenetic Map18E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Malt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319402
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.