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Gene: EIF4A2 (eukaryotic translation initiation factor 4A2) Homo sapiens
Symbol: EIF4A2
Name: eukaryotic translation initiation factor 4A2
Description: Exhibits ATPase activity. Involved in negative regulation of RNA-directed 5'-3' RNA polymerase activity. Localizes to the perinuclear region of cytoplasm; PARTICIPATES IN translation initiation pathway; INTERACTS WITH (-)-demecolcine; (-)-epigallocatechin 3-gallate; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-dependent RNA helicase eIF4A-2; BM-010; DDX2B; eIF-4A-II; EIF4A; eIF4A-II; EIF4F; eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A, isoform 2
Mus musculus (house mouse) : Eif4a2 (eukaryotic translation initiation factor 4A2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Eif4a2 (eukaryotic translation initiation factor 4A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eif4a2 (eukaryotic translation initiation factor 4A2)
Pan paniscus (bonobo/pygmy chimpanzee) : EIF4A2 (eukaryotic translation initiation factor 4A2)
Canis lupus familiaris (dog) : EIF4A2 (eukaryotic translation initiation factor 4A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eif4a2 (eukaryotic translation initiation factor 4A2)
Sus scrofa (pig) : EIF4A2 (eukaryotic translation initiation factor 4A2)
Chlorocebus sabaeus (African green monkey) : EIF4A2 (eukaryotic translation initiation factor 4A2)
Heterocephalus glaber (naked mole-rat) : Eif4a2 (eukaryotic translation initiation factor 4A2)
more info ...
Related Pseudogenes: EIF4A2P1   EIF4A2P2   EIF4A2P3   EIF4A2P4   EIF4A2P5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl3186,783,205 - 186,789,897 (+)Ensembl
GRCh383186,783,577 - 186,789,897 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373186,501,361 - 186,507,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,984,055 - 187,990,380 (+)NCBINCBI36hg18NCBI36
Build 343187,984,086 - 187,990,385NCBI
Celera3184,937,523 - 184,943,848 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,911,038 - 183,917,363 (+)NCBIHuRef
CHM1_13186,464,938 - 186,471,263 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on EIF4A2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319448
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.