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Gene: SRSF3 (serine and arginine rich splicing factor 3) Homo sapiens
Symbol: SRSF3
Name: serine and arginine rich splicing factor 3
Description: Exhibits RNA binding activity. Involved in mRNA export from nucleus and regulation of mRNA splicing, via spliceosome. Localizes to nuclear speck. Biomarker of bipolar disorder and ovary epithelial cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: pre-mRNA splicing factor SRp20; pre-mRNA-splicing factor SRP20; serine/arginine-rich splicing factor 3; SFRS3; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich, 20-kD; SRp20
Mus musculus (house mouse) : Srsf3 (serine and arginine-rich splicing factor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srsf3 (serine and arginine rich splicing factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf3 (serine and arginine rich splicing factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF3 (serine and arginine rich splicing factor 3)
Canis lupus familiaris (dog) : SRSF3 (serine and arginine rich splicing factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf3 (serine and arginine rich splicing factor 3)
Sus scrofa (pig) : SRSF3 (serine and arginine rich splicing factor 3)
Chlorocebus sabaeus (African green monkey) : SRSF3 (serine and arginine rich splicing factor 3)
Heterocephalus glaber (naked mole-rat) : Srsf3 (serine and arginine rich splicing factor 3)
more info ...
Related Pseudogenes: SRSF3P1   SRSF3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl636,594,353 - 36,605,600 (+)EnsemblGRCh38hg38GRCh38
GRCh38636,594,313 - 36,605,600 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37636,562,090 - 36,572,244 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,670,144 - 36,679,187 (+)NCBINCBI36hg18NCBI36
Build 34636,670,143 - 36,679,187NCBI
Celera638,117,136 - 38,127,290 (+)NCBI
Cytogenetic Map6p21.31-p21.2NCBI
HuRef636,280,649 - 36,290,802 (+)NCBIHuRef
CHM1_1636,563,858 - 36,574,011 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SRSF3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319459
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.