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Gene: SLC7A11 (solute carrier family 7 member 11) Homo sapiens
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Symbol: SLC7A11
Name: solute carrier family 7 member 11
CRRD ID: 1319531
Description: Predicted to have L-amino acid transmembrane transporter activity. Involved in response to toxic substance. Localizes to cell surface.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cystine/glutamate transporter; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT
Orthologs:
Mus musculus (house mouse) : Slc7a11 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 11)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc7a11 (solute carrier family 7 member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc7a11 (solute carrier family 7 member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A11 (solute carrier family 7 member 11)
Canis lupus familiaris (dog) : SLC7A11 (solute carrier family 7 member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a11 (solute carrier family 7 member 11)
Sus scrofa (pig) : SLC7A11 (solute carrier family 7 member 11)
Chlorocebus sabaeus (African green monkey) : SLC7A11 (solute carrier family 7 member 11)
Heterocephalus glaber (naked mole-rat) : Slc7a11 (solute carrier family 7 member 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4138,164,097 - 138,242,349 (-)EnsemblGRCh38hg38GRCh38
GRCh384138,164,097 - 138,242,349 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374139,085,248 - 139,163,572 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364139,304,698 - 139,382,953 (-)NCBINCBI36hg18NCBI36
Build 344139,449,092 - 139,520,828NCBI
Celera4136,424,509 - 136,502,906 (-)NCBI
Cytogenetic Map4q28.3NCBI
HuRef4134,820,291 - 134,898,999 (-)NCBIHuRef
CHM1_14139,061,708 - 139,139,961 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC7A11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319531
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.