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Gene: NACC2 (NACC family member 2) Homo sapiens
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Symbol: NACC2
Name: NACC family member 2
Description: Exhibits several functions, including histone deacetylase binding activity; protein homodimerization activity; and transcription corepressor activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Localizes to the mitochondrion; nuclear chromatin; and nucleolus; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BEN domain containing 9; BEND9; BTB (POZ) domain containing 14A; BTB/POZ domain-containing protein 14A; BTBD14; BTBD14A; BTBD31; MGC23427; NAC-2; NACC family member 2, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 2; RBB; repressor with BTB domain and BEN domain; transcription repressor with a BTB domain and a BEN domain
Orthologs:
Mus musculus (house mouse) : Nacc2 (nucleus accumbens associated 2, BEN and BTB (POZ) domain containing)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nacc2 (NACC family member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nacc2 (NACC family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NACC2 (NACC family member 2)
Canis lupus familiaris (dog) : NACC2 (NACC family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nacc2 (NACC family member 2)
Sus scrofa (pig) : NACC2 (NACC family member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,006,537 - 136,095,289 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379138,898,383 - 138,987,131 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,043,023 - 138,126,952 (-)NCBINCBI36hg18NCBI36
Build 349136,129,149 - 136,213,076NCBI
Celera9109,421,076 - 109,505,450 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9108,360,255 - 108,449,736 (-)NCBIHuRef
CHM1_19139,046,411 - 139,135,603 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NACC2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319559
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.