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Gene: NACC2 (NACC family member 2) Homo sapiens
Symbol: NACC2
Name: NACC family member 2
Description: Exhibits several functions, including histone deacetylase binding activity; protein homodimerization activity; and transcription corepressor activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Localizes to the mitochondrion; nuclear chromatin; and nucleolus; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BEN domain containing 9; BEND9; BTB (POZ) domain containing 14A; BTB/POZ domain-containing protein 14A; BTBD14; BTBD14A; BTBD31; MGC23427; NAC-2; NACC family member 2, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 2; RBB; repressor with BTB domain and BEN domain; transcription repressor with a BTB domain and a BEN domain
Mus musculus (house mouse) : Nacc2 (nucleus accumbens associated 2, BEN and BTB (POZ) domain containing)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nacc2 (NACC family member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nacc2 (NACC family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NACC2 (NACC family member 2)
Canis lupus familiaris (dog) : NACC2 (NACC family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nacc2 (NACC family member 2)
Sus scrofa (pig) : NACC2 (NACC family member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389136,006,537 - 136,095,289 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379138,898,383 - 138,987,131 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,043,023 - 138,126,952 (-)NCBINCBI36hg18NCBI36
Build 349136,129,149 - 136,213,076NCBI
Celera9109,421,076 - 109,505,450 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9108,360,255 - 108,449,736 (-)NCBIHuRef
CHM1_19139,046,411 - 139,135,603 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NACC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319559
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.