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Gene: Mdm4 (transformed mouse 3T3 cell double minute 4) Mus musculus
Symbol: Mdm4
Name: transformed mouse 3T3 cell double minute 4
CRRD ID: 1319585
Description: Predicted to have enzyme binding activity. Involved in several processes, including heart development; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of heart rate. Predicted to localize to nucleoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Used to study dilated cardiomyopathy. Orthologous to human MDM4 (MDM4 regulator of p53).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; double minute 4 protein; mdm2-like p53-binding protein; Mdmx; p53-binding protein Mdm4
Homo sapiens (human) : MDM4 (MDM4 regulator of p53)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mdm4 (MDM4 regulator of p53)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdm4 (MDM4 regulator of p53)
Pan paniscus (bonobo/pygmy chimpanzee) : MDM4 (MDM4 regulator of p53)
Canis lupus familiaris (dog) : MDM4 (MDM4 regulator of p53)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdm4 (MDM4 regulator of p53)
Sus scrofa (pig) : MDM4 (MDM4 regulator of p53)
Chlorocebus sabaeus (African green monkey) : MDM4 (MDM4 regulator of p53)
Heterocephalus glaber (naked mole-rat) : Mdm4 (MDM4 regulator of p53)
more info ...
Related Pseudogenes: Mdm4-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1132,959,484 - 133,030,561 (-)EnsemblGRCm38mm10GRCm38
GRCm381132,986,105 - 133,030,587 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371134,886,422 - 134,921,925 (-)NCBIGRCm37mm9NCBIm37
MGSCv361134,817,391 - 134,852,894 (-)NCBImm8
Celera1135,598,842 - 135,634,680 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mdm4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319585
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.