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Gene: Mdm4 (transformed mouse 3T3 cell double minute 4) Mus musculus
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Symbol: Mdm4
Name: transformed mouse 3T3 cell double minute 4
CRRD ID: 1319585
Description: Predicted to have enzyme binding activity. Involved in several processes, including heart development; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of heart rate. Predicted to localize to nucleoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Used to study dilated cardiomyopathy. Orthologous to human MDM4 (MDM4 regulator of p53).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; double minute 4 protein; mdm2-like p53-binding protein; Mdmx; p53-binding protein Mdm4
Orthologs:
Homo sapiens (human) : MDM4 (MDM4 regulator of p53)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mdm4 (MDM4 regulator of p53)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdm4 (MDM4 regulator of p53)
Pan paniscus (bonobo/pygmy chimpanzee) : MDM4 (MDM4 regulator of p53)
Canis lupus familiaris (dog) : MDM4 (MDM4 regulator of p53)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdm4 (MDM4 regulator of p53)
Sus scrofa (pig) : MDM4 (MDM4 regulator of p53)
Chlorocebus sabaeus (African green monkey) : MDM4 (MDM4 regulator of p53)
Heterocephalus glaber (naked mole-rat) : Mdm4 (MDM4 regulator of p53)
more info ...
Related Pseudogenes: Mdm4-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1132,959,484 - 133,030,561 (-)EnsemblGRCm38mm10GRCm38
GRCm381132,986,105 - 133,030,587 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371134,886,422 - 134,921,925 (-)NCBIGRCm37mm9NCBIm37
MGSCv361134,817,391 - 134,852,894 (-)NCBImm8
Celera1135,598,842 - 135,634,680 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mdm4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319585
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.