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Gene: DICER1 (dicer 1, ribonuclease III) Homo sapiens
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Symbol: DICER1
Name: dicer 1, ribonuclease III
Description: Exhibits RNA binding activity; protein domain specific binding activity; and ribonuclease III activity. Involved in several processes, including NIK/NF-kappaB signaling; negative regulation of tumor necrosis factor production; and posttranscriptional gene silencing by RNA. Localizes to the RISC complex; RISC-loading complex; and extracellular exosome. Implicated in multinodular goiter and pleuropulmonary blastoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DCR1; Dicer; dicer 1 ribonuclease III; dicer 1, double-stranded RNA-specific endoribonuclease; dicer 1, ribonuclease type III; Dicer1, Dcr-1 homolog; Dicer1e; endoribonuclease Dicer; GLOW; helicase MOI; helicase with RNAse motif; helicase-moi; HERNA; K12H4.8-LIKE; KIAA0928; MNG1; multinodular goitre 1; RMSE2
Orthologs:
Mus musculus (house mouse) : Dicer1 (dicer 1, ribonuclease type III)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dicer1 (dicer 1 ribonuclease III)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dicer1 (dicer 1, ribonuclease III)
Pan paniscus (bonobo/pygmy chimpanzee) : DICER1 (dicer 1, ribonuclease III)
Canis lupus familiaris (dog) : DICER1 (dicer 1, ribonuclease III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dicer1 (dicer 1, ribonuclease III)
Sus scrofa (pig) : DICER1 (dicer 1, ribonuclease III)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381495,086,228 - 95,158,263 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371495,552,565 - 95,623,759 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361494,622,319 - 94,693,512 (-)NCBINCBI36hg18NCBI36
Build 341494,622,318 - 94,693,512NCBI
Celera1475,608,684 - 75,679,876 (-)NCBI
Cytogenetic Map14q32.13NCBI
HuRef1475,736,521 - 75,807,615 (-)NCBIHuRef
CHM1_11495,490,915 - 95,562,577 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model