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Gene: Sucla2 (succinate-Coenzyme A ligase, ADP-forming, beta subunit) Mus musculus
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Symbol: Sucla2
Name: succinate-Coenzyme A ligase, ADP-forming, beta subunit
Description: Predicted to have succinate-CoA ligase (ADP-forming) activity. Predicted to be involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Localizes to mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study mitochondrial DNA depletion syndrome 5. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Orthologous to human LINC00444 (long intergenic non-protein coding RNA 444); PARTICIPATES IN citric acid cycle pathway; propanoate metabolic pathway; INTERACTS WITH (+)-dexrazoxane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930547K18Rik; A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; SCS-betaA; succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; succinyl-CoA synthetase beta-A chain
Orthologs:
Homo sapiens (human) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sucla2 (succinate-CoA ligase ADP-forming subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sucla2 (succinate-CoA ligase ADP-forming beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Canis lupus familiaris (dog) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sucla2 (succinate-CoA ligase ADP-forming beta subunit)
Sus scrofa (pig) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Chlorocebus sabaeus (African green monkey) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Heterocephalus glaber (naked mole-rat) : Sucla2 (succinate-CoA ligase ADP-forming subunit beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1473,525,319 - 73,596,142 (+)EnsemblGRCm38mm10GRCm38
GRCm381473,552,786 - 73,596,144 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371473,952,593 - 73,995,949 (+)NCBIGRCm37mm9NCBIm37
MGSCv361472,286,941 - 72,330,297 (+)NCBImm8
Celera1471,073,111 - 71,117,384 (+)NCBICelera
Cytogenetic Map14D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sucla2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319722
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.