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Gene: NCF2 (neutrophil cytosolic factor 2) Homo sapiens
Symbol: NCF2
Name: neutrophil cytosolic factor 2
Description: Exhibits protein C-terminus binding activity. Predicted to be involved in superoxide anion generation. Localizes to the cytosol and nucleolus. Implicated in Alzheimer's disease and autosomal recessive chronic granulomatous disease cytochrome b-positive type II.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 67 kDa neutrophil oxidase factor; chronic granulomatous disease, autosomal 2; FLJ93058; NADPH oxidase activator 2; NCF-2; neutrophil cytosol factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil NADPH oxidase factor 2; NOXA2; P67-PHOX; P67PHOX
Mus musculus (house mouse) : Ncf2 (neutrophil cytosolic factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ncf2 (neutrophil cytosolic factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncf2 (neutrophil cytosolic factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF2 (neutrophil cytosolic factor 2)
Canis lupus familiaris (dog) : NCF2 (neutrophil cytosolic factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf2 (neutrophil cytosolic factor 2)
Sus scrofa (pig) : NCF2 (neutrophil cytosolic factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1183,555,563 - 183,590,876 (-)Ensembl
GRCh381183,555,562 - 183,590,914 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371183,524,697 - 183,560,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,791,320 - 181,826,339 (-)NCBINCBI36hg18NCBI36
Build 341180,256,354 - 180,291,668NCBI
Celera1156,635,747 - 156,671,088 (-)NCBI
Cytogenetic Map1q25.3NCBI
HuRef1154,760,563 - 154,795,907 (-)NCBIHuRef
CHM1_11184,947,718 - 184,983,070 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NCF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319760
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.