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Gene: Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8) Mus musculus
Symbol: Ndufs8
Name: NADH:ubiquinone oxidoreductase core subunit S8
Description: Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in cellular respiration; mitochondrial respiratory chain complex I assembly; and response to oxidative stress. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC021616; CI-23kD; complex I-23kD; MGC101957; MGC37950; NADH dehydrogenase (ubiquinone) Fe-S protein 8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY
Homo sapiens (human) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)
Pan paniscus (bonobo/pygmy chimpanzee) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Canis lupus familiaris (dog) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)
Sus scrofa (pig) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Chlorocebus sabaeus (African green monkey) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Heterocephalus glaber (naked mole-rat) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl193,908,863 - 3,912,774 (-)Ensembl
GRCm38193,908,863 - 3,912,774 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,908,870 - 3,912,717 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,908,871 - 3,912,760 (-)NCBImm8
Celera193,789,238 - 3,793,149 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ndufs8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319780
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.