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Gene: Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8) Mus musculus
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Symbol: Ndufs8
Name: NADH:ubiquinone oxidoreductase core subunit S8
Description: Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in cellular respiration; mitochondrial respiratory chain complex I assembly; and response to oxidative stress. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC021616; CI-23kD; complex I-23kD; MGC101957; MGC37950; NADH dehydrogenase (ubiquinone) Fe-S protein 8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY
Orthologs:
Homo sapiens (human) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)
Pan paniscus (bonobo/pygmy chimpanzee) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Canis lupus familiaris (dog) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)
Sus scrofa (pig) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Chlorocebus sabaeus (African green monkey) : NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8)
Heterocephalus glaber (naked mole-rat) : Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl193,908,863 - 3,912,774 (-)Ensembl
GRCm38193,908,863 - 3,912,774 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,908,870 - 3,912,717 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,908,871 - 3,912,760 (-)NCBImm8
Celera193,789,238 - 3,793,149 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ndufs8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319780
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.