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Gene: Vangl2 (VANGL planar cell polarity 2) Mus musculus
Symbol: Vangl2
Name: VANGL planar cell polarity 2
Description: Involved in several processes, including Wnt signaling pathway, planar cell polarity pathway; animal organ development; and morphogenesis of an epithelium. Localizes to several cellular components, including the COPII-coated ER to Golgi transport vesicle; lateral plasma membrane; and stress fiber. Used to study neural tube defect. Human ortholog(s) of this gene implicated in neural tube defect. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system epithelium; and sensory organ. Orthologous to human VANGL2 (VANGL planar cell polarity protein 2); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, the planar cell polarity pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aldrin; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C530001F03Rik; loop tail associated protein; loop-tail; loop-tail protein 1; loop-tail-associated protein; Lootl; Lp; Lpp1; Ltap; ska17; ska; stbm; strabismus; van Gogh-like protein 2; vang (van gogh)-like 2; vang-like 2 (van gogh, Drosophila); vang-like protein 2; Vang1l2
Homo sapiens (human) : VANGL2 (VANGL planar cell polarity protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vangl2 (VANGL planar cell polarity protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vangl2 (VANGL planar cell polarity protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : VANGL2 (VANGL planar cell polarity protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vangl2 (VANGL planar cell polarity protein 2)
Sus scrofa (pig) : VANGL2 (VANGL planar cell polarity protein 2)
Chlorocebus sabaeus (African green monkey) : VANGL2 (VANGL planar cell polarity protein 2)
Heterocephalus glaber (naked mole-rat) : Vangl2 (VANGL planar cell polarity protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1172,000,960 - 172,028,444 (-)EnsemblGRCm38mm10GRCm38
GRCm381172,000,960 - 172,027,318 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371173,934,502 - 173,957,399 (-)NCBIGRCm37mm9NCBIm37
MGSCv361173,841,046 - 173,863,943 (-)NCBImm8
Celera1174,856,349 - 174,879,265 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Vangl2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319788
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.