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Gene: INTU (inturned planar cell polarity protein) Homo sapiens
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Symbol: INTU
Name: inturned planar cell polarity protein
Description: Predicted to be involved in several processes, including cilium assembly; limb development; and regulation of smoothened signaling pathway. Localizes to the ciliary basal body and motile cilium. Implicated in asphyxiating thoracic dystrophy and orofaciodigital syndrome XVII; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ciliogenesis and planar polarity effector 4; CPLANE4; FLJ41326; homolog of inturned; INT; inturned planar cell polarity effector homolog; KIAA1284; OFD17; PDZ domain containing 6; PDZ domain-containing protein 6; PDZD6; PDZK6; protein inturned; SRTD20
Orthologs:
Mus musculus (house mouse) : Intu (inturned planar cell polarity protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Intu (inturned planar cell polarity protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Intu (inturned planar cell polarity protein)
Pan paniscus (bonobo/pygmy chimpanzee) : INTU (inturned planar cell polarity protein)
Canis lupus familiaris (dog) : INTU (inturned planar cell polarity protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Intu (inturned planar cell polarity protein)
Sus scrofa (pig) : INTU (inturned planar cell polarity protein)
Chlorocebus sabaeus (African green monkey) : INTU (inturned planar cell polarity protein)
Heterocephalus glaber (naked mole-rat) : Intu (inturned planar cell polarity protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl4127,623,271 - 127,726,737 (+)EnsemblGRCh38hg38GRCh38
GRCh384127,623,271 - 127,726,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374128,554,087 - 128,637,934 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364128,773,570 - 128,857,380 (+)NCBINCBI36hg18NCBI36
Celera4125,933,098 - 126,016,912 (+)NCBI
Cytogenetic Map4q28.1NCBI
HuRef4124,281,813 - 124,365,618 (+)NCBIHuRef
CHM1_14128,530,549 - 128,614,401 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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RNA-SEQ Expression

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Additional Information

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Nomenclature History
 
More on INTU
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319793
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.