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Gene: LTBR (lymphotoxin beta receptor) Homo sapiens
Symbol: LTBR
Name: lymphotoxin beta receptor
Description: Exhibits identical protein binding activity and ubiquitin protein ligase binding activity. Involved in cellular response to mechanical stimulus and positive regulation of signal transduction. Localizes to the Golgi apparatus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD18; D12S370; LT-BETA-R; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF-R-III; TNF-RIII; TNFCR; TNFR superfamily, member 3; TNFR-III; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3; tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III
Mus musculus (house mouse) : Ltbr (lymphotoxin B receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ltbr (lymphotoxin beta receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ltbr (lymphotoxin beta receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LTBR (lymphotoxin beta receptor)
Canis lupus familiaris (dog) : LTBR (lymphotoxin beta receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ltbr (lymphotoxin beta receptor)
Sus scrofa (pig) : LTBR (lymphotoxin beta receptor)
Chlorocebus sabaeus (African green monkey) : LTBR (lymphotoxin beta receptor)
Heterocephalus glaber (naked mole-rat) : Ltbr (lymphotoxin beta receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl126,375,045 - 6,391,571 (+)Ensembl
GRCh38126,375,160 - 6,391,571 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,484,534 - 6,500,737 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,363,618 - 6,370,993 (+)NCBINCBI36hg18NCBI36
Build 34126,363,617 - 6,370,993NCBI
Celera128,110,613 - 8,117,993 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,338,399 - 6,354,609 (+)NCBIHuRef
CHM1_1126,483,716 - 6,499,925 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LTBR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319795
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.