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Gene: EXO1 (exonuclease 1) Homo sapiens
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Symbol: EXO1
Name: exonuclease 1
Description: Exhibits DNA binding activity and deoxyribonuclease activity. Involved in DNA recombination and mismatch repair. Localizes to nuclear body and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: exonuclease I; HEX1; hExo1; hExoI; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1
Orthologs:
Mus musculus (house mouse) : Exo1 (exonuclease 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Exo1 (exonuclease 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exo1 (exonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EXO1 (exonuclease 1)
Canis lupus familiaris (dog) : EXO1 (exonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Exo1 (exonuclease 1)
Sus scrofa (pig) : EXO1 (exonuclease 1)
Chlorocebus sabaeus (African green monkey) : EXO1 (exonuclease 1)
Heterocephalus glaber (naked mole-rat) : Exo1 (exonuclease 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1241,847,967 - 241,895,148 (+)EnsemblGRCh38hg38GRCh38
GRCh381241,847,967 - 241,889,939 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371242,011,491 - 242,053,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361240,078,158 - 240,119,671 (+)NCBINCBI36hg18NCBI36
Build 341238,337,575 - 238,379,088NCBI
Celera1215,267,055 - 215,308,778 (+)NCBI
Cytogenetic Map1q43NCBI
HuRef1212,470,280 - 212,512,011 (+)NCBIHuRef
CHM1_11243,284,062 - 243,325,806 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EXO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319820
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.