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Gene: Exo1 (exonuclease 1) Mus musculus
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Symbol: Exo1
Name: exonuclease 1
Description: ENCODES a protein that exhibits chromatin binding; 5'-3' exodeoxyribonuclease activity (ortholog); 5'-3' exonuclease activity (ortholog); INVOLVED IN humoral immune response mediated by circulating immunoglobulin; isotype switching; somatic hypermutation of immunoglobulin genes; PARTICIPATES IN homologous recombination pathway of double-strand break repair; mismatch repair pathway; ASSOCIATED WITH abnormal chiasmata formation; abnormal chromosome stability; abnormal class switch recombination; ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-dexrazoxane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730442G03Rik; exonuclease I; mExo1; Msa; RIKEN cDNA 5730442G03 gene
Orthologs:
Homo sapiens (human) : EXO1 (exonuclease 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Exo1 (exonuclease 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exo1 (exonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EXO1 (exonuclease 1)
Canis lupus familiaris (dog) : EXO1 (exonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Exo1 (exonuclease 1)
Sus scrofa (pig) : EXO1 (exonuclease 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381175,880,768 - 175,911,396 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371177,810,909 - 177,841,527 (+)NCBIGRCm37mm9NCBIm37
MGSCv361177,717,473 - 177,745,968 (+)NCBImm8
Celera1182,960,192 - 182,991,063 (+)NCBICelera
Cytogenetic Map1 H4NCBI
cM Map181.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Exo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319821
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.