Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TOP3B (DNA topoisomerase III beta) Homo sapiens
Analyze
Symbol: TOP3B
Name: DNA topoisomerase III beta
Description: Exhibits RNA binding activity. Predicted to be involved in DNA topological change. Predicted to localize to the nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA topoisomerase 3-beta-1; DNA topoisomerase III beta-1; FLJ39376; TOP3B1; topoisomerase (DNA) III beta; topoisomerase III beta
Orthologs:
Mus musculus (house mouse) : Top3b (topoisomerase (DNA) III beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Top3b (DNA topoisomerase III beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Top3b (DNA topoisomerase III beta)
Pan paniscus (bonobo/pygmy chimpanzee) : TOP3B (DNA topoisomerase III beta)
Canis lupus familiaris (dog) : TOP3B (DNA topoisomerase III beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Top3b (DNA topoisomerase III beta)
Sus scrofa (pig) : TOP3B (DNA topoisomerase III beta)
more info ...
Related Pseudogenes: TOP3BP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,957,025 - 21,982,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372222,311,397 - 22,337,219 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,641,403 - 20,667,147 (-)NCBINCBI36hg18NCBI36
Build 342220,635,957 - 20,661,701NCBI
Celera226,128,944 - 6,154,663 (-)NCBI
Cytogenetic Map22q11.22NCBI
HuRef225,268,479 - 5,294,196 (-)NCBIHuRef
CHM1_12222,311,495 - 22,337,313 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TOP3B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319825
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.