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Gene: Alkbh5 (alkB homolog 5, RNA demethylase) Mus musculus
Symbol: Alkbh5
Name: alkB homolog 5, RNA demethylase
Description: Exhibits RNA N6-methyladenosine dioxygenase activity. Involved in oxidative single-stranded RNA demethylation; regulation of mRNA stability; and spermatogenesis. Localizes to the nuclear speck. Is expressed in brain. Orthologous to human ALKBH5 (alkB homolog 5, RNA demethylase); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abh5; alkB, alkylation repair homolog 5; alkylated DNA repair protein alkB homolog 5; alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; AW050020; AW215868; E130207K11; expressed sequence AW215868; Ofoxd; oxoglutarate and iron-dependent oxygenase domain containing; probable alpha-ketoglutarate-dependent dioxygenase ABH5; RNA demethylase ALKBH5
Homo sapiens (human) : ALKBH5 (alkB homolog 5, RNA demethylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Alkbh5 (alkB homolog 5, RNA demethylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alkbh5 (alkB homolog 5, RNA demethylase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALKBH5 (alkB homolog 5, RNA demethylase)
Canis lupus familiaris (dog) : ALKBH5 (alkB homolog 5, RNA demethylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alkbh5 (alkB homolog 5, RNA demethylase)
Sus scrofa (pig) : ALKBH5 (alkB homolog 5, RNA demethylase)
Chlorocebus sabaeus (African green monkey) : ALKBH5 (alkB homolog 5, RNA demethylase)
Heterocephalus glaber (naked mole-rat) : Alkbh5 (alkB homolog 5, RNA demethylase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1160,536,381 - 60,558,512 (+)EnsemblGRCm38mm10GRCm38
GRCm381160,537,683 - 60,558,512 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371160,351,185 - 60,372,014 (+)NCBIGRCm37mm9NCBIm37
MGSCv361160,354,173 - 60,372,092 (+)NCBImm8
Celera1165,862,595 - 65,871,990 (-)NCBICelera
Cytogenetic Map11B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Alkbh5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319866
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.