Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ITM2C (integral membrane protein 2C) Homo sapiens
Analyze
Symbol: ITM2C
Name: integral membrane protein 2C
Description: Exhibits amyloid-beta binding activity. Involved in negative regulation of neuron projection development and neuron differentiation. Localizes to several cellular components, including the Golgi apparatus; lysosome; and perinuclear region of cytoplasm; INTERACTS WITH 17beta-estradiol; 2-methylcholine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BRI3; BRICD2C; BRICHOS domain containing 2C; cerebral protein 14; E25; E25C; hRPC.1050_D_4; integral membrane protein 3; ITM3; transmembrane protein BRI3
Orthologs:
Mus musculus (house mouse) : Itm2c (integral membrane protein 2C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itm2c (integral membrane protein 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itm2c (integral membrane protein 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : ITM2C (integral membrane protein 2C)
Canis lupus familiaris (dog) : ITM2C (integral membrane protein 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itm2c (integral membrane protein 2C)
Sus scrofa (pig) : ITM2C (integral membrane protein 2C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,864,185 - 230,879,254 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372231,729,546 - 231,743,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,437,865 - 231,452,207 (+)NCBINCBI36hg18NCBI36
Build 342231,555,125 - 231,569,467NCBI
Celera2225,506,038 - 225,520,369 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2223,571,781 - 223,586,111 (+)NCBIHuRef
CHM1_12231,735,141 - 231,749,777 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ITM2C
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319877
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.