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Gene: TAB2 (TGF-beta activated kinase 1 (MAP3K7) binding protein 2) Homo sapiens
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Symbol: TAB2
Name: TGF-beta activated kinase 1 (MAP3K7) binding protein 2
CRRD ID: 1319911
Description: Exhibits K63-linked polyubiquitin modification-dependent protein binding activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of protein kinase activity; and response to lipopolysaccharide. Predicted to localize to several cellular components, including cytosol; endosome membrane; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; TAK1-binding protein 2; TGF-beta activated kinase 1/MAP3K7 binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6149,218,641 - 149,411,613 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl6149,217,926 - 149,245,554 (+)EnsemblGRCh38hg38GRCh38
GRCh386149,217,926 - 149,411,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376149,639,436 - 149,732,747 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366149,680,756 - 149,774,440 (+)NCBINCBI36hg18NCBI36
Build 346149,680,755 - 149,774,440NCBI
Celera6150,374,542 - 150,467,843 (+)NCBI
Cytogenetic Map6q25.1NCBI
HuRef6147,206,396 - 147,299,504 (+)NCBIHuRef
CHM1_16149,803,803 - 149,997,500 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

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Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TAB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319911
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.