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Gene: GPR68 (G protein-coupled receptor 68) Homo sapiens
Symbol: GPR68
Name: G protein-coupled receptor 68
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in cellular response to pH. Predicted to localize to the integral component of plasma membrane. Implicated in amelogenesis imperfecta.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI2A6; G-protein coupled receptor 68; GPR12A; MGC111379; MGC156983; OGR1; ovarian cancer G protein-coupled receptor, 1; ovarian cancer G-protein coupled receptor 1; sphingosylphosphorylcholine receptor
Mus musculus (house mouse) : Gpr68 (G protein-coupled receptor 68)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr68 (G protein-coupled receptor 68)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr68 (G protein-coupled receptor 68)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR68 (G protein-coupled receptor 68)
Canis lupus familiaris (dog) : GPR68 (G protein-coupled receptor 68)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr68 (G protein-coupled receptor 68)
Sus scrofa (pig) : GPR68 (G protein-coupled receptor 68)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1491,232,532 - 91,253,925 (-)Ensembl
GRCh381491,232,532 - 91,264,581 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371491,698,876 - 91,730,898 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361490,768,629 - 90,789,977 (-)NCBINCBI36hg18NCBI36
Build 341490,769,964 - 90,790,022NCBI
Celera1471,747,337 - 71,768,677 (-)NCBI
Cytogenetic Map14q32.11NCBI
HuRef1471,875,167 - 71,896,408 (-)NCBIHuRef
CHM1_11491,636,649 - 91,657,972 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPR68
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319965
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.