Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tfeb (transcription factor EB) Mus musculus
Symbol: Tfeb
Name: transcription factor EB
CRRD ID: 1319998
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including defense response to Gram-negative bacterium; embryonic placenta development; and positive regulation of transcription by RNA polymerase II. Localizes to cytoplasm and transcription regulator complex. Colocalizes with nucleus. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and gut gland. Orthologous to human TFEB (transcription factor EB); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine; arachidonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHe3; bHLHe35; Tcfeb
Homo sapiens (human) : TFEB (transcription factor EB)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfeb (transcription factor EB)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfeb (transcription factor EB)
Pan paniscus (bonobo/pygmy chimpanzee) : TFEB (transcription factor EB)
Canis lupus familiaris (dog) : TFEB (transcription factor EB)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfeb (transcription factor EB)
Sus scrofa (pig) : TFEB (transcription factor EB)
Chlorocebus sabaeus (African green monkey) : TFEB (transcription factor EB)
Heterocephalus glaber (naked mole-rat) : Tfeb (transcription factor EB)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391748,047,962 - 48,103,341 (+)NCBI
GRCm381747,737,037 - 47,792,416 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1747,737,030 - 47,792,419 (+)EnsemblGRCm38mm10GRCm38
MGSCv371747,873,986 - 47,929,365 (+)NCBIGRCm37mm9NCBIm37
MGSCv361747,248,935 - 47,255,607 (+)NCBImm8
Celera1751,174,084 - 51,229,512 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tfeb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1319998
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.