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Gene: Adam8 (a disintegrin and metallopeptidase domain 8) Mus musculus
Symbol: Adam8
Name: a disintegrin and metallopeptidase domain 8
Description: This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: a disintegrin and metalloprotease domain (ADAM) 8; a disintegrin and metalloprotease domain 8; ADAM 8; CD156; CD156a; cell surface antigen MS2; disintegrin and metalloproteinase domain-containing protein 8; E430039A18Rik; macrophage cysteine-rich glycoprotein; MS2
Homo sapiens (human) : ADAM8 (ADAM metallopeptidase domain 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adam8 (ADAM metallopeptidase domain 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam8 (ADAM metallopeptidase domain 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM8 (ADAM metallopeptidase domain 8)
Canis lupus familiaris (dog) : ADAM8 (ADAM metallopeptidase domain 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam8 (ADAM metallopeptidase domain 8)
Sus scrofa (pig) : ADAM8 (ADAM metallopeptidase domain 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm387139,978,932 - 139,993,121 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377147,164,840 - 147,178,387 (-)NCBIGRCm37mm9NCBIm37
MGSCv367139,830,261 - 139,843,808 (-)NCBImm8
Celera7139,782,794 - 139,796,326 (-)NCBICelera
Cytogenetic Map7 F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adam8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320020
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.