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Gene: PLA2G2E (phospholipase A2 group IIE) Homo sapiens
Symbol: PLA2G2E
Name: phospholipase A2 group IIE
Description: Predicted to have calcium-dependent phospholipase A2 activity and phospholipid binding activity. Predicted to be involved in negative regulation of T cell proliferation and phospholipid metabolic process. Predicted to localize to the extracellular region; PARTICIPATES IN arachidonic acid metabolic pathway; glutamate signaling pathway; glycerophospholipid metabolic pathway; INTERACTS WITH aflatoxin B1; bis(2-ethylhexyl) phthalate; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GIIE sPLA2; group IIE secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 2E; phospholipase A2, group IIE; sPLA2-IIE
Mus musculus (house mouse) : Pla2g2e (phospholipase A2, group IIE)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pla2g2e (phospholipase A2, group IIE)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g2e (phospholipase A2 group IIE)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G2E (phospholipase A2 group IIE)
Canis lupus familiaris (dog) : LOC487399 (group IIE secretory phospholipase A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g2e (phospholipase A2 group IIE)
Sus scrofa (pig) : PLA2G2E (phospholipase A2 group IIE)
Chlorocebus sabaeus (African green monkey) : PLA2G2E (phospholipase A2 group IIE)
Heterocephalus glaber (naked mole-rat) : Pla2g2e (phospholipase A2 group IIE)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl119,920,009 - 19,923,617 (-)EnsemblGRCh38hg38GRCh38
GRCh38119,920,009 - 19,923,617 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37120,246,800 - 20,250,110 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,119,387 - 20,122,697 (-)NCBINCBI36hg18NCBI36
Build 34119,992,105 - 19,995,416NCBI
Celera118,573,636 - 18,576,946 (-)NCBI
Cytogenetic Map1p36.13NCBI
HuRef118,492,424 - 18,495,734 (-)NCBIHuRef
CHM1_1120,356,341 - 20,359,651 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PLA2G2E
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320041
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.