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Gene: Ank1 (ankyrin 1, erythroid) Mus musculus
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Symbol: Ank1
Name: ankyrin 1, erythroid
Description: Predicted to have cytoskeletal protein binding activity; enzyme binding activity; and ion channel binding activity. Involved in several processes, including erythrocyte development; iron ion homeostasis; and porphyrin-containing compound biosynthetic process. Localizes to cortical cytoskeleton; membrane; and spectrin-associated cytoskeleton. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; retina; and skeletal muscle. Used to study hereditary spherocytosis type 1 and malaria. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ank-1; ankyrin-1; erythrocyte ankyrin; nb; normoblastic anemia; pale
Orthologs:
Homo sapiens (human) : ANK1 (ankyrin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ank1 (ankyrin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ank1 (ankyrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANK1 (ankyrin 1)
Canis lupus familiaris (dog) : ANK1 (ankyrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ank1 (ankyrin 1)
Sus scrofa (pig) : ANK1 (ankyrin 1)
Chlorocebus sabaeus (African green monkey) : ANK1 (ankyrin 1)
Heterocephalus glaber (naked mole-rat) : Ank1 (ankyrin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl822,974,844 - 23,150,497 (+)EnsemblGRCm38mm10GRCm38
GRCm38822,974,836 - 23,150,501 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37824,085,354 - 24,260,968 (+)NCBIGRCm37mm9NCBIm37
MGSCv36824,523,820 - 24,616,041 (+)NCBImm8
Celera824,465,487 - 24,646,749 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ank1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320056
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.