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Gene: Ank1 (ankyrin 1, erythroid) Mus musculus
Symbol: Ank1
Name: ankyrin 1, erythroid
Description: Predicted to have cytoskeletal protein binding activity; enzyme binding activity; and ion channel binding activity. Involved in several processes, including erythrocyte development; iron ion homeostasis; and porphyrin-containing compound biosynthetic process. Localizes to cortical cytoskeleton; membrane; and spectrin-associated cytoskeleton. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; retina; and skeletal muscle. Used to study hereditary spherocytosis type 1 and malaria. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ank-1; ankyrin-1; erythrocyte ankyrin; nb; normoblastic anemia; pale
Homo sapiens (human) : ANK1 (ankyrin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ank1 (ankyrin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ank1 (ankyrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANK1 (ankyrin 1)
Canis lupus familiaris (dog) : ANK1 (ankyrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ank1 (ankyrin 1)
Sus scrofa (pig) : ANK1 (ankyrin 1)
Chlorocebus sabaeus (African green monkey) : ANK1 (ankyrin 1)
Heterocephalus glaber (naked mole-rat) : Ank1 (ankyrin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl822,974,844 - 23,150,497 (+)EnsemblGRCm38mm10GRCm38
GRCm38822,974,836 - 23,150,501 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37824,085,354 - 24,260,968 (+)NCBIGRCm37mm9NCBIm37
MGSCv36824,523,820 - 24,616,041 (+)NCBImm8
Celera824,465,487 - 24,646,749 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ank1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320056
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.