Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Magel2 (melanoma antigen, family L, 2) Mus musculus
Symbol: Magel2
Name: melanoma antigen, family L, 2
Description: Predicted to have ubiquitin-protein transferase activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of actin nucleation; and regulation of circadian rhythm. Localizes to cytoplasm and nucleus. Predicted to colocalize with retromer complex. Used to study Prader-Willi syndrome. Human ortholog(s) of this gene implicated in Schaaf-Yang syndrome. Is expressed in several structures, including brain; egg cylinder; reproductive system; turbinate bone primordium; and vertebral axis musculature. Orthologous to human MAGEL2 (MAGE family member L2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Mage-l2; MAGE-like protein 2; melanoma antigen-like gene 2; NDNL1; necdin-like 1; nM15; ns7
Homo sapiens (human) : MAGEL2 (MAGE family member L2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Magel2 (MAGE family member L2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Magel2 (MAGE family member L2)
Pan paniscus (bonobo/pygmy chimpanzee) : MAGEL2 (MAGE family member L2)
Canis lupus familiaris (dog) : MAGEL2 (MAGE family member L2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Magel2 (MAGE family member L2)
Sus scrofa (pig) : MAGEL2 (MAGE family member L2)
Chlorocebus sabaeus (African green monkey) : MAGEL2 (MAGE family member L2)
Heterocephalus glaber (naked mole-rat) : Magel2 (MAGE family member L2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl762,377,010 - 62,381,640 (+)EnsemblGRCm38mm10GRCm38
GRCm38762,376,979 - 62,381,640 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37769,521,865 - 69,526,526 (+)NCBIGRCm37mm9NCBIm37
MGSCv36751,738,184 - 51,742,845 (+)NCBImm8
MGSCv36762,255,929 - 62,260,590 (+)NCBImm8
Cytogenetic Map7CNCBI
cM Map734.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Magel2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320099
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.