Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: E2f3 (E2F transcription factor 3) Mus musculus
Analyze
Symbol: E2f3
Name: E2F transcription factor 3
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity. Predicted to contribute to DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of fat cell proliferation; positive regulation of cell population proliferation; and positive regulation of transcription, DNA-templated. Predicted to localize to the RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human E2F3 (E2F transcription factor 3); PARTICIPATES IN cell cycle pathway, mitotic; ceramide signaling pathway; chronic myeloid leukemia pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-nitroquinoline N-oxide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E2F-3; E2f3a; E2F3b; mKIAA0075; transcription factor E2F3
Orthologs:
Homo sapiens (human) : E2F3 (E2F transcription factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : E2f3 (E2F transcription factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f3 (E2F transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F3 (E2F transcription factor 3)
Canis lupus familiaris (dog) : E2F3 (E2F transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f3 (E2F transcription factor 3)
Sus scrofa (pig) : E2F3 (E2F transcription factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381329,906,575 - 29,986,064 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371329,998,444 - 30,077,932 (-)NCBIGRCm37mm9NCBIm37
MGSCv361329,917,237 - 29,993,528 (-)NCBImm8
Celera1330,125,315 - 30,204,809 (-)NCBICelera
Cytogenetic Map13 A3.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on E2f3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320123
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.