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Gene: ATG4B (autophagy related 4B cysteine peptidase) Homo sapiens
Symbol: ATG4B
Name: autophagy related 4B cysteine peptidase
Description: Exhibits cysteine-type peptidase activity and endopeptidase activity. Involved in autophagy; protein delipidation; and proteolysis. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APG4 autophagy 4 homolog B; apg4 autophagy 4 homolog b (s. cerevisiae); APG4B; ATG4 autophagy related 4 homolog B; AUT-like 1 cysteine endopeptidase; AUTL1; autophagin-1; autophagy related 4B, cysteine peptidase; autophagy-related cysteine endopeptidase 1; autophagy-related protein 4 homolog B; cysteine protease ATG4B; hAPG4B; MGC1353
Mus musculus (house mouse) : Atg4b (autophagy related 4B, cysteine peptidase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atg4b (autophagy related 4B, cysteine peptidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atg4b (autophagy related 4B cysteine peptidase)
Pan paniscus (bonobo/pygmy chimpanzee) : ATG4B (autophagy related 4B cysteine peptidase)
Canis lupus familiaris (dog) : ATG4B (autophagy related 4B cysteine peptidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atg4b (autophagy related 4B cysteine peptidase)
Sus scrofa (pig) : ATG4B (autophagy related 4B cysteine peptidase)
Chlorocebus sabaeus (African green monkey) : ATG4B (autophagy related 4B cysteine peptidase)
Heterocephalus glaber (naked mole-rat) : Atg4b (autophagy related 4B cysteine peptidase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2241,637,213 - 241,673,857 (+)EnsemblGRCh38hg38GRCh38
GRCh382241,637,659 - 241,673,857 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,576,775 - 242,613,272 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362242,225,700 - 242,261,945 (+)NCBINCBI36hg18NCBI36
Celera2236,248,753 - 236,285,072 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2234,345,804 - 234,368,653 (+)NCBIHuRef
CHM1_12242,583,163 - 242,619,336 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ATG4B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320126
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.