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Gene: Rhbdf2 (rhomboid 5 homolog 2) Mus musculus
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Symbol: Rhbdf2
Name: rhomboid 5 homolog 2
Description: Involved in negative regulation of protein secretion. Localizes to endoplasmic reticulum membrane. Used to study nonepidermolytic palmoplantar keratoderma. Human ortholog(s) of this gene implicated in palmoplantar keratoderma-esophageal carcinoma syndrome. Orthologous to human RHBDF2 (rhomboid 5 homolog 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; 4-nonylphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4732465I17Rik; cub; inactive rhomboid protein 2; iRhom2; Rhbdl6; rhomboid family member 2; rhomboid veinlet-like protein 6; rhomboid, veinlet-like 6; rhomboid-like protein 6; rhomboid-related protein
Orthologs:
Homo sapiens (human) : RHBDF2 (rhomboid 5 homolog 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rhbdf2 (rhomboid 5 homolog 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rhbdf2 (rhomboid 5 homolog 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RHBDF2 (rhomboid 5 homolog 2)
Canis lupus familiaris (dog) : RHBDF2 (rhomboid 5 homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rhbdf2 (rhomboid 5 homolog 2)
Sus scrofa (pig) : RHBDF2 (rhomboid 5 homolog 2)
Chlorocebus sabaeus (African green monkey) : RHBDF2 (rhomboid 5 homolog 2)
Heterocephalus glaber (naked mole-rat) : Rhbdf2 (rhomboid 5 homolog 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl11116,598,165 - 116,627,019 (-)EnsemblGRCm38mm10GRCm38
GRCm3811116,598,148 - 116,626,960 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711116,459,479 - 116,488,333 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611116,414,259 - 116,443,109 (-)NCBImm8
Celera11128,368,470 - 128,397,196 (-)NCBICelera
Cytogenetic Map11E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Rhbdf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320183
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.