Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MVB12B (multivesicular body subunit 12B) Homo sapiens
Symbol: MVB12B
Name: multivesicular body subunit 12B
Description: Exhibits lipid binding activity. Involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Localizes to several cellular components, including the cytosol; endosome; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C9orf28; chromosome 9 open reading frame 28; ESCRT-I complex subunit MVB12B; FAM125B; family with sequence similarity 125, member B; FLJ00001
Mus musculus (house mouse) : Mvb12b (multivesicular body subunit 12B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mvb12b (multivesicular body subunit 12B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mvb12b (multivesicular body subunit 12B)
Pan paniscus (bonobo/pygmy chimpanzee) : MVB12B (multivesicular body subunit 12B)
Canis lupus familiaris (dog) : MVB12B (multivesicular body subunit 12B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mvb12b (multivesicular body subunit 12B)
Sus scrofa (pig) : MVB12B (multivesicular body subunit 12B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389126,326,829 - 126,507,040 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379129,089,123 - 129,269,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369128,128,949 - 128,309,140 (+)NCBINCBI36hg18NCBI36
Celera999,743,357 - 99,922,950 (+)NCBI
Cytogenetic Map9q33.3NCBI
HuRef998,706,516 - 98,885,863 (+)NCBIHuRef
CHM1_19129,240,183 - 129,420,105 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MVB12B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320196
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.