Gene: HDAC1 (histone deacetylase 1) Homo sapiens
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Symbol: HDAC1
Name: histone deacetylase 1
Description: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686H12203; GON-10; HD1; KDAC1; reduced potassium dependency, yeast homolog-like 1; RPD3; RPD3L1
Orthologs:
Mus musculus (house mouse) : Hdac1 (histone deacetylase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hdac1 (histone deacetylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac1 (histone deacetylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC1 (histone deacetylase 1)
Canis lupus familiaris (dog) : HDAC1 (histone deacetylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac1 (histone deacetylase 1)
Sus scrofa (pig) : HDAC1 (histone deacetylase 1)
more info ...
Related Pseudogenes: HDAC1P1   HDAC1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38132,292,103 - 32,333,628 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37132,757,708 - 32,799,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36132,530,295 - 32,571,811 (+)NCBINCBI36hg18NCBI36
Build 34132,426,800 - 32,468,317NCBI
Celera131,028,175 - 31,069,691 (+)NCBI
Cytogenetic Map1p35.2-p35.1NCBI
HuRef130,873,184 - 30,914,532 (+)NCBIHuRef
CHM1_1132,873,153 - 32,914,668 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HDAC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320330
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.