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Gene: MED21 (mediator complex subunit 21) Homo sapiens
Symbol: MED21
Name: mediator complex subunit 21
Description: Exhibits transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to the mediator complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hSrb7; mediator of RNA polymerase II transcription subunit 21; RNA polymerase II complex component SRB7; RNA polymerase II holoenzyme component SRB7; RNAPII complex component SRB7; SRB7; SRB7 suppressor of RNA polymerase B homolog; SURB7
Mus musculus (house mouse) : Med21 (mediator complex subunit 21)  MGI  Alliance
Rattus norvegicus (Norway rat) : Med21 (mediator complex subunit 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med21 (mediator complex subunit 21)
Pan paniscus (bonobo/pygmy chimpanzee) : MED21 (mediator complex subunit 21)
Canis lupus familiaris (dog) : MED21 (mediator complex subunit 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med21 (mediator complex subunit 21)
Sus scrofa (pig) : MED21 (mediator complex subunit 21)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381227,022,522 - 27,030,673 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371227,175,455 - 27,183,606 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361227,066,750 - 27,073,949 (+)NCBINCBI36hg18NCBI36
Build 341227,066,749 - 27,073,949NCBI
Celera1232,321,635 - 32,328,835 (+)NCBI
Cytogenetic Map12p11.23NCBI
HuRef1226,945,525 - 26,953,676 (+)NCBIHuRef
CHM1_11227,140,470 - 27,148,626 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MED21
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320392
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.