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Gene: Fgd2 (FYVE, RhoGEF and PH domain containing 2) Mus musculus
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Symbol: Fgd2
Name: FYVE, RhoGEF and PH domain containing 2
CRRD ID: 1320400
Description: Exhibits Rho guanyl-nucleotide exchange factor activity and phosphatidylinositol phosphate binding activity. Involved in positive regulation of JUN kinase activity. Localizes to early endosome; nucleus; and ruffle. Orthologous to human FGD2 (FYVE, RhoGEF and PH domain containing 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: faciogenital dysplasia homolog 2; faciogenital dysplasia protein 2; Fgd1 family, member 2; Fgd2-like protein; FYVE, RhoGEF and PH domain-containing protein 2; t-complex distorter 2; Tcd-2; Tcd2; tcs; tcs-; tcs-2; tcs2; ZFYVE4
Orthologs:
Homo sapiens (human) : FGD2 (FYVE, RhoGEF and PH domain containing 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgd2 (FYVE, RhoGEF and PH domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgd2 (FYVE, RhoGEF and PH domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGD2 (FYVE, RhoGEF and PH domain containing 2)
Canis lupus familiaris (dog) : FGD2 (FYVE, RhoGEF and PH domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgd2 (FYVE, RhoGEF and PH domain containing 2)
Sus scrofa (pig) : FGD2 (FYVE, RhoGEF and PH domain containing 2)
Chlorocebus sabaeus (African green monkey) : FGD2 (FYVE, RhoGEF and PH domain containing 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,579,878 - 29,598,509 (+)NCBI
GRCm381729,360,904 - 29,379,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,360,914 - 29,379,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv371729,497,859 - 29,516,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361729,087,926 - 29,106,565 (+)NCBImm8
Celera1729,903,505 - 29,922,630 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fgd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320400
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.