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Gene: Tbx18 (T-box18) Mus musculus
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Symbol: Tbx18
Name: T-box18
Description: Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; anterior/posterior pattern specification; and positive regulation of cell population proliferation. Localizes to the nucleus. Colocalizes with the Tle3-Aes complex. Human ortholog(s) of this gene implicated in CAKUT2. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart and pericardium; sensory organ; and vibrissa. Orthologous to human TBX18 (T-box transcription factor 18); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810012F10Rik; 2810404D13Rik; T-box protein 18; T-box transcription factor TBX18
Orthologs:
Homo sapiens (human) : TBX18 (T-box transcription factor 18)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbx18 (T-box transcription factor 18)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx18 (T-box transcription factor 18)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX18 (T-box transcription factor 18)
Canis lupus familiaris (dog) : TBX18 (T-box transcription factor 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx18 (T-box transcription factor 18)
Sus scrofa (pig) : TBX18 (T-box transcription factor 18)
Chlorocebus sabaeus (green monkey) : TBX18 (T-box transcription factor 18)
Heterocephalus glaber (naked mole-rat) : Tbx18 (T-box transcription factor 18)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl987,702,800 - 87,731,260 (-)Ensembl
GRCm38987,702,800 - 87,731,260 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37987,597,635 - 87,626,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv36987,502,145 - 87,529,206 (-)NCBImm8
Celera984,762,550 - 84,791,101 (-)NCBICelera
Cytogenetic Map9 E3.1NCBI
cM Map947.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tbx18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320423
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.