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Gene: Tbx18 (T-box18) Mus musculus
Symbol: Tbx18
Name: T-box18
Description: Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; anterior/posterior pattern specification; and positive regulation of cell population proliferation. Localizes to the nucleus. Colocalizes with the Tle3-Aes complex. Human ortholog(s) of this gene implicated in CAKUT2. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart and pericardium; sensory organ; and vibrissa. Orthologous to human TBX18 (T-box transcription factor 18); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810012F10Rik; 2810404D13Rik; T-box protein 18; T-box transcription factor TBX18
Homo sapiens (human) : TBX18 (T-box transcription factor 18)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbx18 (T-box transcription factor 18)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx18 (T-box transcription factor 18)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX18 (T-box transcription factor 18)
Canis lupus familiaris (dog) : TBX18 (T-box transcription factor 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx18 (T-box transcription factor 18)
Sus scrofa (pig) : TBX18 (T-box transcription factor 18)
Chlorocebus sabaeus (green monkey) : TBX18 (T-box transcription factor 18)
Heterocephalus glaber (naked mole-rat) : Tbx18 (T-box transcription factor 18)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl987,702,800 - 87,731,260 (-)Ensembl
GRCm38987,702,800 - 87,731,260 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37987,597,635 - 87,626,095 (-)NCBIGRCm37mm9NCBIm37
MGSCv36987,502,145 - 87,529,206 (-)NCBImm8
Celera984,762,550 - 84,791,101 (-)NCBICelera
Cytogenetic Map9 E3.1NCBI
cM Map947.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tbx18
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320423
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.