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Gene: Pla2g2d (phospholipase A2, group IID) Mus musculus
Symbol: Pla2g2d
Name: phospholipase A2, group IID
Description: Exhibits heparan sulfate proteoglycan binding activity and heparin binding activity. Involved in CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation and negative regulation of T cell proliferation. Predicted to localize to the cytoplasm and extracellular region. Is expressed in several structures, including heart; hemolymphoid system gland; lung; skin; and small intestine. Orthologous to human PLA2G2D (phospholipase A2 group IID); PARTICIPATES IN glycerophospholipid metabolic pathway; arachidonic acid metabolic pathway; glutamate signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; benzo[a]pyrene; benzo[b]fluoranthene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GIID; GIID sPLA2; group IID secretory phospholipase A2; MGC130437; mGIID; phosphatidylcholine 2-acylhydrolase 2D; PLA2IID; secretory-type PLA, stroma-associated homolog; sPLA2-IID; Splash
Homo sapiens (human) : PLA2G2D (phospholipase A2 group IID)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pla2g2d (phospholipase A2, group IID)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g2d (phospholipase A2 group IID)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G2D (phospholipase A2 group IID)
Canis lupus familiaris (dog) : PLA2G2D (phospholipase A2 group IID)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g2d (phospholipase A2 group IID)
Sus scrofa (pig) : PLA2G2D (phospholipase A2 group IID)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384138,775,735 - 138,782,052 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374138,331,650 - 138,338,058 (+)NCBIGRCm37mm9NCBIm37
MGSCv364138,047,811 - 138,054,219 (+)NCBImm8
Celera4140,558,983 - 140,565,391 (+)NCBICelera
Cytogenetic Map4 D3NCBI
cM Map470.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pla2g2d
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320433
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.