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Gene: BRD7 (bromodomain containing 7) Homo sapiens
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Symbol: BRD7
Name: bromodomain containing 7
Description: Exhibits several functions, including lysine-acetylated histone binding activity; p53 binding activity; and transcription coregulator activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; positive regulation of histone acetylation; and regulation of transcription, DNA-templated. Localizes to the cytosol and nucleoplasm. Implicated in acute myeloid leukemia. Biomarker of acute myeloid leukemia; carcinoma (multiple); and malignant glioma (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 75 kDa bromodomain protein; BP75; bromodomain protein; bromodomain-containing 7; bromodomain-containing protein 7; CELTIX1; NAG4; protein CELTIX-1
Orthologs:
Mus musculus (house mouse) : Brd7 (bromodomain containing 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Brd7 (bromodomain containing 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brd7 (bromodomain containing 7)
Pan paniscus (bonobo/pygmy chimpanzee) : BRD7 (bromodomain containing 7)
Canis lupus familiaris (dog) : BRD7 (bromodomain containing 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brd7 (bromodomain containing 7)
Sus scrofa (pig) : BRD7 (bromodomain containing 7)
more info ...
Related Pseudogenes: BRD7P1   BRD7P2   BRD7P3   BRD7P4   BRD7P5   BRD7P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381650,315,957 - 50,368,988 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371650,352,929 - 50,402,845 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361648,910,442 - 48,960,330 (-)NCBINCBI36hg18NCBI36
Build 341648,910,441 - 48,960,330NCBI
Celera1634,867,347 - 34,917,271 (-)NCBI
Cytogenetic Map16q12.1NCBI
HuRef1636,240,844 - 36,290,809 (-)NCBIHuRef
CHM1_11651,760,032 - 51,809,939 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on BRD7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320478
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.