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Gene: Crb1 (crumbs family member 1, photoreceptor morphogenesis associated) Mus musculus
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Symbol: Crb1
Name: crumbs family member 1, photoreceptor morphogenesis associated
Description: Predicted to have calcium ion binding activity. Involved in eye photoreceptor cell development and plasma membrane organization. Localizes to the microvillus and plasma membrane. Used to study Leber congenital amaurosis 8 and retinitis pigmentosa 12. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Leber congenital amaurosis 8; cone-rod dystrophy; retinitis pigmentosa; and retinitis pigmentosa 12. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human CRB1 (crumbs cell polarity complex component 1); INTERACTS WITH carbon nanotube; isoprenaline; potassium dichromate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 7530426H14Rik; A930008G09Rik; crumbs homolog 1
Orthologs:
Homo sapiens (human) : CRB1 (crumbs cell polarity complex component 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Crb1 (crumbs cell polarity complex component 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crb1 (crumbs cell polarity complex component 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CRB1 (crumbs cell polarity complex component 1)
Canis lupus familiaris (dog) : CRB1 (crumbs cell polarity complex component 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crb1 (crumbs cell polarity complex component 1)
Sus scrofa (pig) : CRB1 (crumbs cell polarity complex component 1)
Chlorocebus sabaeus (African green monkey) : CRB1 (crumbs cell polarity complex component 1)
Heterocephalus glaber (naked mole-rat) : Crb1 (crumbs cell polarity complex component 1)
more info ...
Related Pseudogenes: Gm11498   Gm12805   Gm12948   Gm13452   Gm14609   Gm14655   Gm14656   Gm14824   Gm14971   Gm14977   Gm14981   Gm15022   Gm15073   Gm15116   Gm15158   Gm17070   Gm18426   Gm18427   Gm18428   Gm18429   Gm18430   Gm18431   Gm18434   Gm18437   Gm18440   Gm18443   Gm18444   Gm18447   Gm18448   Gm18449   Gm18450   Gm18451   Gm18452   Gm18453   Gm18455   Gm18456   Gm18458   Gm18459   Gm18460   Gm18461   Gm18462   Gm18463   Gm18464   Gm18465   Gm18466   Gm18467   Gm18468   Gm18469   Gm18470   Gm18471   Gm18472   Gm18474   Gm18475   Gm18481   Gm18482   Gm18483   Gm18484   Gm18485   Gm18486   Gm18487   Gm18488   Gm18489   Gm18495   Gm18496   Gm18499   Gm18500   Gm18501   Gm18502   Gm18504   Gm18509   Gm18510   Gm18512   Gm18513   Gm18514   Gm18517   Gm18518   Gm18519   Gm18520   Gm18521   Gm18522   Gm18523   Gm18524   Gm18525   Gm18526   Gm18527   Gm18528   Gm18530   Gm18531   Gm18532   Gm18533   Gm18543   Gm18544   Gm2505   Gm3092   Gm38420   Gm4115  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1139,197,056 - 139,377,100 (-)EnsemblGRCm38mm10GRCm38
GRCm381139,176,649 - 139,379,316 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371141,094,831 - 141,273,653 (-)NCBIGRCm37mm9NCBIm37
MGSCv361141,014,754 - 141,193,452 (-)NCBImm8
Celera1141,833,551 - 142,013,612 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map160.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Crb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320565
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.