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Gene: HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) Homo sapiens
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Symbol: HNRNPDL
Name: heterogeneous nuclear ribonucleoprotein D like
Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A+U-rich element RNA binding factor; AU-rich element RNA-binding factor; heterogeneous nuclear ribonucleoprotein D-like; HNRNP; hnRNP D-like; hnRNP DL; HNRPDL; JKT41-binding protein; JKTBP; JKTBP2; laAUF1; LGMD1G; LGMDD3; limb girdle muscular dystrophy 1G (autosomal dominant)
Orthologs:
Related Pseudogenes: HNRNPDLP1   HNRNPDLP2   HNRNPDLP3   HNRNPDLP4   HNRNPDLP5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38482,422,564 - 82,430,225 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37483,343,717 - 83,351,378 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36483,563,371 - 83,570,402 (-)NCBINCBI36hg18NCBI36
Celera480,635,634 - 80,642,665 (-)NCBI
Cytogenetic Map4q21.22NCBI
HuRef479,085,093 - 79,092,735 (-)NCBIHuRef
CHM1_1483,320,226 - 83,327,863 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HNRNPDL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320569
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.