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Gene: ARRDC1 (arrestin domain containing 1) Homo sapiens
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Symbol: ARRDC1
Name: arrestin domain containing 1
Description: Exhibits several functions, including arrestin family protein binding activity; protein binding activity, bridging involved in substrate recognition for ubiquitination; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular protein metabolic process; extracellular vesicle biogenesis; and negative regulation of Notch signaling pathway. Localizes to the cytoplasmic vesicle; extracellular vesicle; and plasma membrane; INTERACTS WITH 17beta-estradiol; cisplatin; cobalt dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-arrestin 1; arrestin domain-containing protein 1; MGC40555; RP11-48C7.5
Orthologs:
Mus musculus (house mouse) : Arrdc1 (arrestin domain containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arrdc1 (arrestin domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arrdc1 (arrestin domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ARRDC1 (arrestin domain containing 1)
Canis lupus familiaris (dog) : ARRDC1 (arrestin domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arrdc1 (arrestin domain containing 1)
Sus scrofa (pig) : ARRDC1 (arrestin domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,605,640 - 137,615,360 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379140,500,092 - 140,509,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,619,917 - 139,629,633 (+)NCBINCBI36hg18NCBI36
Build 349137,775,942 - 137,785,646NCBI
Celera9111,023,757 - 111,033,473 (+)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9109,962,058 - 109,971,771 (+)NCBIHuRef
CHM1_19140,648,823 - 140,658,543 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ARRDC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320585
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.