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Gene: ARRDC1 (arrestin domain containing 1) Homo sapiens
Symbol: ARRDC1
Name: arrestin domain containing 1
Description: Exhibits several functions, including arrestin family protein binding activity; protein binding activity, bridging involved in substrate recognition for ubiquitination; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular protein metabolic process; extracellular vesicle biogenesis; and negative regulation of Notch signaling pathway. Localizes to the cytoplasmic vesicle; extracellular vesicle; and plasma membrane; INTERACTS WITH 17beta-estradiol; cisplatin; cobalt dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-arrestin 1; arrestin domain-containing protein 1; MGC40555; RP11-48C7.5
Mus musculus (house mouse) : Arrdc1 (arrestin domain containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arrdc1 (arrestin domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arrdc1 (arrestin domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ARRDC1 (arrestin domain containing 1)
Canis lupus familiaris (dog) : ARRDC1 (arrestin domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arrdc1 (arrestin domain containing 1)
Sus scrofa (pig) : ARRDC1 (arrestin domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389137,605,640 - 137,615,360 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379140,500,092 - 140,509,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,619,917 - 139,629,633 (+)NCBINCBI36hg18NCBI36
Build 349137,775,942 - 137,785,646NCBI
Celera9111,023,757 - 111,033,473 (+)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9109,962,058 - 109,971,771 (+)NCBIHuRef
CHM1_19140,648,823 - 140,658,543 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ARRDC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320585
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.