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Gene: Fktn (fukutin) Mus musculus
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Symbol: Fktn
Name: fukutin
Description: Predicted to have transferase activity. Predicted to be involved in negative regulation of JNK cascade; negative regulation of cell population proliferation; and protein O-linked mannosylation. Localizes to the Golgi apparatus. Used to study Fukuyama congenital muscular dystrophy and muscular dystrophy-dystroglycanopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy (multiple) and muscular dystrophy (multiple). Is expressed in several structures, including central nervous system; future brain; genitourinary system; retina; and spleen. Orthologous to human FKTN (fukutin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D830030O17Rik; Fcmd; Fukuyama type congenital muscular dystrophy (fukutin); Fukuyama type congenital muscular dystrophy homolog; ribitol-5-phosphate transferase
Orthologs:
Homo sapiens (human) : FKTN (fukutin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fktn (fukutin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fktn (fukutin)
Pan paniscus (bonobo/pygmy chimpanzee) : FKTN (fukutin)
Canis lupus familiaris (dog) : FKTN (fukutin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fktn (fukutin)
Sus scrofa (pig) : FKTN (fukutin)
Chlorocebus sabaeus (African green monkey) : FKTN (fukutin)
Heterocephalus glaber (naked mole-rat) : Fktn (fukutin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl453,713,998 - 53,777,890 (+)Ensembl
GRCm38453,714,107 - 53,765,785 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37453,727,054 - 53,776,143 (+)NCBIGRCm37mm9NCBIm37
MGSCv36453,735,282 - 53,784,371 (+)NCBImm8
Celera453,671,147 - 53,720,238 (+)NCBICelera
Cytogenetic Map4 B2NCBI
cM Map428.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fktn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320792
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.