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Gene: Fktn (fukutin) Mus musculus
Symbol: Fktn
Name: fukutin
Description: Predicted to have transferase activity. Predicted to be involved in negative regulation of JNK cascade; negative regulation of cell population proliferation; and protein O-linked mannosylation. Localizes to the Golgi apparatus. Used to study Fukuyama congenital muscular dystrophy and muscular dystrophy-dystroglycanopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy (multiple) and muscular dystrophy (multiple). Is expressed in several structures, including central nervous system; future brain; genitourinary system; retina; and spleen. Orthologous to human FKTN (fukutin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D830030O17Rik; Fcmd; Fukuyama type congenital muscular dystrophy (fukutin); Fukuyama type congenital muscular dystrophy homolog; ribitol-5-phosphate transferase
Homo sapiens (human) : FKTN (fukutin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fktn (fukutin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fktn (fukutin)
Pan paniscus (bonobo/pygmy chimpanzee) : FKTN (fukutin)
Canis lupus familiaris (dog) : FKTN (fukutin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fktn (fukutin)
Sus scrofa (pig) : FKTN (fukutin)
Chlorocebus sabaeus (African green monkey) : FKTN (fukutin)
Heterocephalus glaber (naked mole-rat) : Fktn (fukutin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl453,713,998 - 53,777,890 (+)Ensembl
GRCm38453,714,107 - 53,765,785 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37453,727,054 - 53,776,143 (+)NCBIGRCm37mm9NCBIm37
MGSCv36453,735,282 - 53,784,371 (+)NCBImm8
Celera453,671,147 - 53,720,238 (+)NCBICelera
Cytogenetic Map4 B2NCBI
cM Map428.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fktn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320792
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.