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Gene: ARPC4 (actin related protein 2/3 complex subunit 4) Homo sapiens
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Symbol: ARPC4
Name: actin related protein 2/3 complex subunit 4
Description: Exhibits enzyme binding activity. Contributes to actin filament binding activity and protein binding activity, bridging. Involved in Arp2/3 complex-mediated actin nucleation. Localizes to the Arp2/3 protein complex. Biomarker of Down syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: actin related protein 2/3 complex subunit 4, 20kDa; actin related protein 2/3 complex, subunit 4, 20kDa; actin-related protein 2/3 complex subunit 4; ARC20; arp2/3 complex 20 kDa subunit; Arp2/3 protein complex subunit p20; MGC13544; p20-Arc
Orthologs:
Mus musculus (house mouse) : Arpc4 (actin related protein 2/3 complex, subunit 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arpc4 (actin related protein 2/3 complex, subunit 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arpc4 (actin related protein 2/3 complex subunit 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ARPC4 (actin related protein 2/3 complex subunit 4)
Canis lupus familiaris (dog) : ARPC4 (actin related protein 2/3 complex subunit 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arpc4 (actin related protein 2/3 complex subunit 4)
Sus scrofa (pig) : ARPC4 (actin related protein 2/3 complex subunit 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl39,792,495 - 9,807,726 (+)Ensembl
GRCh3839,792,495 - 9,807,724 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3739,834,082 - 9,848,789 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3639,809,227 - 9,823,789 (+)NCBINCBI36hg18NCBI36
Build 3439,809,733 - 9,823,784NCBI
Celera39,768,927 - 9,783,489 (+)NCBI
Cytogenetic Map3p25.3NCBI
HuRef39,770,526 - 9,785,132 (+)NCBIHuRef
CHM1_139,784,371 - 9,798,980 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARPC4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320803
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.