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Gene: Rnf111 (ring finger 111) Mus musculus
Symbol: Rnf111
Name: ring finger 111
Description: Exhibits ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of macromolecule metabolic process; and positive regulation of transforming growth factor beta receptor signaling pathway. Localizes to the cytoplasm; nucleus; and protein-containing complex. Is expressed in several structures, including heart; nervous system; testis; and urinary system. Orthologous to human RNF111 (ring finger protein 111); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH benzo[a]pyrene; pirinixic acid; silver atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ARK; Arkadia; E3 ubiquitin-protein ligase Arkadia; RING finger protein 111; RING-type E3 ubiquitin transferase Arkadia
Homo sapiens (human) : RNF111 (ring finger protein 111)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rnf111 (ring finger protein 111)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf111 (ring finger protein 111)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF111 (ring finger protein 111)
Canis lupus familiaris (dog) : RNF111 (ring finger protein 111)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf111 (ring finger protein 111)
Sus scrofa (pig) : RNF111 (ring finger protein 111)
Chlorocebus sabaeus (African green monkey) : RNF111 (ring finger protein 111)
Heterocephalus glaber (naked mole-rat) : Rnf111 (ring finger protein 111)
more info ...
Related Pseudogenes: Gm6162  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl970,425,424 - 70,503,725 (-)Ensembl
GRCm38970,425,424 - 70,503,840 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37970,273,236 - 70,351,532 (-)NCBIGRCm37mm9NCBIm37
MGSCv36970,224,593 - 70,302,889 (-)NCBImm8
Celera967,641,547 - 67,720,771 (-)NCBICelera
Cytogenetic Map9 DNCBI
cM Map939.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rnf111
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320806
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.