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Gene: Tmprss3 (transmembrane protease, serine 3) Mus musculus
Symbol: Tmprss3
Name: transmembrane protease, serine 3
CRRD ID: 1320862
Description: Predicted to have sodium channel regulator activity. Involved in sensory perception of sound. Localizes to endoplasmic reticulum and neuronal cell body. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 8 and sensorineural hearing loss. Orthologous to human TMPRSS3 (transmembrane serine protease 3); INTERACTS WITH N-nitrosodiethylamine; paracetamol; tungsten.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC130589; transmembrane protease serine 3; transmembrane proteinase serine 3
Homo sapiens (human) : TMPRSS3 (transmembrane serine protease 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tmprss3 (transmembrane serine protease 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmprss3 (transmembrane serine protease 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TMPRSS3 (transmembrane serine protease 3)
Canis lupus familiaris (dog) : TMPRSS3 (transmembrane serine protease 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmprss3 (transmembrane serine protease 3)
Sus scrofa (pig) : TMPRSS3 (transmembrane serine protease 3)
Chlorocebus sabaeus (African green monkey) : TMPRSS3 (transmembrane serine protease 3)
Heterocephalus glaber (naked mole-rat) : Tmprss3 (transmembrane serine protease 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391731,398,237 - 31,419,478 (-)NCBI
GRCm381731,179,263 - 31,200,504 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,179,265 - 31,198,977 (-)EnsemblGRCm38mm10GRCm38
MGSCv371731,316,210 - 31,335,919 (-)NCBIGRCm37mm9NCBIm37
MGSCv361730,906,277 - 30,924,761 (-)NCBImm8
Celera1732,096,501 - 32,116,151 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tmprss3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320862
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.