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Gene: Ddb2 (damage specific DNA binding protein 2) Mus musculus
Symbol: Ddb2
Name: damage specific DNA binding protein 2
Description: Predicted to contribute to damaged DNA binding activity and ubiquitin-protein transferase activity. Involved in pyrimidine dimer repair. Predicted to localize to the Cul4B-RING E3 ubiquitin ligase complex; cell junction; and nucleoplasm. Used to study xeroderma pigmentosum group E. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2); PARTICIPATES IN nucleotide excision repair pathway; p53 signaling pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; belinostat.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610043A19Rik; damage-specific DNA-binding protein 2; DNA damage-binding protein 2; MGC117576
Homo sapiens (human) : DDB2 (damage specific DNA binding protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ddb2 (damage specific DNA binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddb2 (damage specific DNA binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DDB2 (damage specific DNA binding protein 2)
Canis lupus familiaris (dog) : DDB2 (damage specific DNA binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddb2 (damage specific DNA binding protein 2)
Sus scrofa (pig) : DDB2 (damage specific DNA binding protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38291,211,545 - 91,237,132 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37291,051,736 - 91,077,223 (-)NCBIGRCm37mm9NCBIm37
MGSCv36291,012,695 - 91,037,821 (-)NCBImm8
Celera292,597,053 - 92,622,532 (-)NCBICelera
Cytogenetic Map2 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ddb2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320907
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.