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Gene: Fermt3 (fermitin family member 3) Mus musculus
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Symbol: Fermt3
Name: fermitin family member 3
Description: Exhibits integrin binding activity. Involved in several processes, including integrin activation; platelet aggregation; and regulation of cell-cell adhesion mediated by integrin. Localizes to the podosome. Used to study leukocyte adhesion deficiency 3. Human ortholog(s) of this gene implicated in leukocyte adhesion deficiency 1 and leukocyte adhesion deficiency 3. Is expressed in several structures, including genitourinary system; hemolymphoid system; intestine; liver; and lung. Orthologous to human FERMT3 (fermitin family member 3); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C79673; fermitin family homolog 3; Kindlin3; MGC36836; MGC38286; unc-112-related protein 2
Orthologs:
Homo sapiens (human) : FERMT3 (fermitin family member 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fermt3 (fermitin family member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fermt3 (fermitin family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FERMT3 (fermitin family member 3)
Canis lupus familiaris (dog) : FERMT3 (fermitin family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fermt3 (fermitin family member 3)
Sus scrofa (pig) : FERMT3 (fermitin family member 3)
Chlorocebus sabaeus (green monkey) : FERMT3 (fermitin family member 3)
Heterocephalus glaber (naked mole-rat) : Fermt3 (fermitin family member 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,998,958 - 7,019,469 (-)Ensembl
GRCm38196,998,958 - 7,019,469 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37197,073,448 - 7,093,959 (-)NCBIGRCm37mm9NCBIm37
MGSCv36197,066,022 - 7,086,479 (-)NCBImm8
Celera196,776,072 - 6,796,571 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Fermt3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320913
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.