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Gene: ALX4 (ALX homeobox 4) Homo sapiens
Symbol: ALX4
Name: ALX homeobox 4
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in hair follicle development. Localizes to the nucleoplasm. Implicated in craniosynostosis and parietal foramina.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aristaless-like homeobox 4; CRS5; FND2; FPP; homeobox protein aristaless-like 4; homeodomain transcription factor ALX4; KIAA1788; PFM; PFM1; PFM2
Mus musculus (house mouse) : Alx4 (aristaless-like homeobox 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Alx4 (ALX homeobox 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alx4 (ALX homeobox 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ALX4 (ALX homeobox 4)
Canis lupus familiaris (dog) : ALX4 (ALX homeobox 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alx4 (ALX homeobox 4)
Sus scrofa (pig) : ALX4 (ALX homeobox 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1144,260,440 - 44,310,139 (-)Ensembl
GRCh381144,260,440 - 44,310,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371144,282,278 - 44,331,735 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,242,734 - 44,288,292 (-)NCBINCBI36hg18NCBI36
Build 341144,242,733 - 44,288,292NCBI
Celera1144,429,565 - 44,479,005 (-)NCBI
Cytogenetic Map11p11.2NCBI
HuRef1143,991,253 - 44,040,694 (-)NCBIHuRef
CHM1_11144,281,300 - 44,330,733 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ALX4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1320963
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.