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Gene: MFF (mitochondrial fission factor) Homo sapiens
Symbol: MFF
Name: mitochondrial fission factor
CRRD ID: 1321011
Description: Exhibits protein homodimerization activity. Involved in several processes, including mitochondrion organization; peroxisome fission; and positive regulation of mitochondrion organization. Localizes to mitochondrial membrane; peroxisome; and protein-containing complex. Predicted to colocalize with mitochondrial membrane and synaptic vesicle membrane. Implicated in brain disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C2orf33; DKFZp666J168; EMPF2; GL004; MGC110913; mitochondrial fission factor homolog B
Mus musculus (house mouse) : Mff (mitochondrial fission factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mff (mitochondrial fission factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mff (mitochondrial fission factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MFF (mitochondrial fission factor)
Canis lupus familiaris (dog) : MFF (mitochondrial fission factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mff (mitochondrial fission factor)
Sus scrofa (pig) : MFF (mitochondrial fission factor)
Chlorocebus sabaeus (African green monkey) : MFF (mitochondrial fission factor)
Heterocephalus glaber (naked mole-rat) : Mff (mitochondrial fission factor)
more info ...
Related Pseudogenes: AC234775.1   LOC100420262   MFFP1   MFFP2   MFFP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2227,325,151 - 227,357,836 (+)EnsemblGRCh38hg38GRCh38
GRCh382227,325,233 - 227,357,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372228,189,867 - 228,222,552 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,900,472 - 227,930,793 (+)NCBINCBI36hg18NCBI36
Build 342228,017,732 - 228,048,052NCBI
Celera2221,961,362 - 221,991,712 (+)NCBI
Cytogenetic Map2q36.3NCBI
HuRef2220,033,273 - 220,065,950 (+)NCBIHuRef
CHM1_12228,195,676 - 228,228,351 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MFF
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321011
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.