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Gene: MFF (mitochondrial fission factor) Homo sapiens
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Symbol: MFF
Name: mitochondrial fission factor
Description: Exhibits protein homodimerization activity. Involved in several processes, including apoptotic mitochondrial changes; mitochondrion morphogenesis; and positive regulation of mitochondrion organization. Localizes to the integral component of mitochondrial membrane; mitochondrial outer membrane; and peroxisome. Implicated in brain disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C2orf33; DKFZp666J168; EMPF2; GL004; MGC110913; mitochondrial fission factor homolog B
Orthologs:
Mus musculus (house mouse) : Mff (mitochondrial fission factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mff (mitochondrial fission factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mff (mitochondrial fission factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MFF (mitochondrial fission factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mff (mitochondrial fission factor)
Sus scrofa (pig) : MFF (mitochondrial fission factor)
more info ...
Related Pseudogenes: MFFP1   MFFP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382227,325,233 - 227,357,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372228,189,867 - 228,222,552 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,900,472 - 227,930,793 (+)NCBINCBI36hg18NCBI36
Build 342228,017,732 - 228,048,052NCBI
Celera2221,961,362 - 221,991,712 (+)NCBI
Cytogenetic Map2q36.3NCBI
HuRef2220,033,273 - 220,065,950 (+)NCBIHuRef
CHM1_12228,195,676 - 228,228,351 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MFF
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321011
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.