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Gene: Tfap2a (transcription factor AP-2, alpha) Mus musculus
Symbol: Tfap2a
Name: transcription factor AP-2, alpha
Description: Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coregulator activity. Involved in several processes, including animal organ development; nervous system development; and regulation of transcription by RNA polymerase II. Localizes to nucleus. Used to study orofacial cleft. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome. Is expressed in several structures, including branchial arch; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human TFAP2A (transcription factor AP-2 alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; activator protein 2; AP-2; Ap-2 (a); AP-2 alpha; AP-2 transcription factor; Ap2; AP2-alpha; AP2alpha; Ap2tf; Tcfap2a; transcription factor AP-2; transcription factor AP-2-alpha
Homo sapiens (human) : TFAP2A (transcription factor AP-2 alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfap2a (transcription factor AP-2 alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfap2a (transcription factor AP-2 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : TFAP2A (transcription factor AP-2 alpha)
Canis lupus familiaris (dog) : TFAP2A (transcription factor AP-2 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfap2a (transcription factor AP-2 alpha)
Sus scrofa (pig) : TFAP2A (transcription factor AP-2 alpha)
Chlorocebus sabaeus (African green monkey) : TFAP2A (transcription factor AP-2 alpha)
Heterocephalus glaber (naked mole-rat) : Tfap2a (transcription factor AP-2 alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1340,715,302 - 40,738,376 (-)EnsemblGRCm38mm10GRCm38
GRCm381340,713,802 - 40,738,238 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371340,811,044 - 40,829,192 (-)NCBIGRCm37mm9NCBIm37
MGSCv361340,727,706 - 40,745,894 (-)NCBImm8
Celera1341,797,334 - 41,815,714 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1320.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tfap2a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321068
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.