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Gene: MARK4 (microtubule affinity regulating kinase 4) Homo sapiens
Symbol: MARK4
Name: microtubule affinity regulating kinase 4
Description: Exhibits protein kinase activity and tubulin binding activity. Involved in several processes, including microtubule bundle formation; positive regulation of protein localization to centrosome; and regulation of organelle organization. Localizes to several cellular components, including dendrite; microtubule cytoskeleton; and midbody.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ12177; FLJ90097; KIAA1860; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase like 1; MAP/microtubule affinity-regulating kinase-like 1; MARK4 serine/threonine protein kinase; MARK4L; MARK4S; MARKL1; MARKL1L; Nbla00650; PAR-1D; putative protein product of Nbla00650
Mus musculus (house mouse) : Mark4 (MAP/microtubule affinity regulating kinase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mark4 (microtubule affinity regulating kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mark4 (microtubule affinity regulating kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : MARK4 (microtubule affinity regulating kinase 4)
Canis lupus familiaris (dog) : MARK4 (microtubule affinity regulating kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mark4 (microtubule affinity regulating kinase 4)
Sus scrofa (pig) : MARK4 (microtubule affinity regulating kinase 4)
Chlorocebus sabaeus (African green monkey) : MARK4 (microtubule affinity regulating kinase 4)
Heterocephalus glaber (naked mole-rat) : Mark4 (microtubule affinity regulating kinase 4)
more info ...
Related Pseudogenes: MARK2P17  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1945,079,288 - 45,305,284 (+)EnsemblGRCh38hg38GRCh38
GRCh381945,251,271 - 45,305,284 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371945,754,516 - 45,808,541 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,446,682 - 50,500,381 (+)NCBINCBI36hg18NCBI36
Build 341950,446,681 - 50,500,381NCBI
Celera1942,560,416 - 42,614,109 (+)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1942,186,730 - 42,240,375 (+)NCBIHuRef
CHM1_11945,757,812 - 45,811,842 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MARK4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321076
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.